Characterization of a hypoallergenic wheat line lacking ω-5 gliadin
نویسندگان
چکیده
منابع مشابه
Diagnostic value of IgE antibodies to ω-5 gliadin, HMW-glutenin and gliadins in wheat challenged children
Background Wheat is one of the six most common foods causing allergy in children. Tests used in clinical practice to diagnose wheat allergy have limited value in predicting allergic reactions when eating wheat. A poor correlation between the outcome of oral wheat-challenges and the levels of IgE-antibodies (IgE-ab) to wheat has been observed. The wheat allergen ω-5 gliadin has been found to fac...
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Wheat gliadin has been found by two different methods to contain three N-terminal histidine residues for each molecular weight of 27,000. Trace amounts of N-terminal aspartic acid, glutamic acid, alanine, valine, and serine were also detected in the preparation used. Hydrolysis in boiling hydrochloric acid partially destroyed the di-2,4-dinitrophenyl derivative of histidine. Losses of from 5% t...
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The utility of mining DNA sequence data to understand the structure and expression of cereal prolamin genes is demonstrated by the identification of a new class of wheat prolamins. This previously unrecognized wheat prolamin class, given the name δ-gliadins, is the most direct ortholog of barley γ3-hordeins. Phylogenetic analysis shows that the orthologous δ-gliadins and γ3-hordeins form a dist...
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[b]Abstract Introduction and objective[/b]. Gluten proteins (gliadins and glutenins) are polymorphic wheat storage proteins of allergenic properties. Significant differences in chemical composition between both protein groups allow to expect highly specific immunological response of individual subunits and fractions in reactions with IgE sera of people allergic to wheat. The aim of these studie...
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ژورنال
عنوان ژورنال: Allergology International
سال: 2016
ISSN: 1323-8930
DOI: 10.1016/j.alit.2016.03.002